Transforming cardiac CT diagnostics.

Turning routine CT scans into advanced coronary diagnostics. Earlier, safer detection of coronary artery disease, without contrast agents or specialized imaging workflows.

  • Starts with A routine CAC scan Non-contrast. Already part of standard screening.
  • Delivers A Virtual CCTA AI-generated coronary imaging. No contrast required.

Built on five years of NIH-funded cardiac imaging research at Weill Cornell Medicine.

NIH — National Institutes of Health Weill Cornell Medicine Weill Cornell Medicine Enterprise Innovation

How Lucentia works

From a routine scan to the coronary arteries.

One scan a patient may already have. Three steps to a coronary read that used to require contrast, a dedicated protocol and a specialized workflow.

  1. 01

    Routine CAC scan

    A non-contrast coronary artery calcium scan is the starting point. It is fast, low-dose and widely available.

  2. 02

    Lucentia AI enhances the scan

    Models trained on proprietary cardiac imaging data turn the routine scan into a high-fidelity coronary read, with no workflow changes.

  3. 03

    Virtual CCTA, no contrast

    An AI-generated CCTA from the CAC scan, ready for review, with no contrast agent and no specialized imaging workflow.

Lucentia Virtual CCTA generated from the same CAC scan, showing the contrast-enhanced coronary anatomy.
Routine non-contrast CAC scan.
CAC scan · non-contrast Lucentia Virtual CCTA
Drag to compare. Same patient, same routine CAC acquisition. The Virtual CCTA is generated by Lucentia, no contrast injected.

Technology

Earlier, safer detection of coronary artery disease.

At Lucentia, we harness advanced artificial intelligence and proprietary cardiac imaging data to enable earlier, safer detection of coronary artery disease. Our technology transforms routine CT scans into high-fidelity coronary insights, reducing reliance on contrast agents and specialized imaging workflows while improving access to advanced cardiac diagnostics.

Not your average scan

Coronary detail, from a routine scan.

Feature CAC scan CCTA Lucentia Virtual CCTA
Contrast agent injectedNoneRequiredNone
Coronary vessel imagingCalcium onlyContrast-enhancedAI-generated
Specialized imaging workflowNot neededRequiredNot needed
Starts from a routine screening scanYesSeparate acquisitionYes
Disease stage detectedLate stageEarly → late stageEarly → late stage

CCTA: coronary computed tomography angiography, the contrast-enhanced reference for imaging the coronary lumen.

Built with

  • Weill Cornell Medicine
  • NewYork-Presbyterian
  • Emory Healthcare
  • Hôpital Bichat Claude-Bernard, AP-HP
  • CHU Ambroise Paré
  • Mount Sinai
  • UCSF — University of California, San Francisco

Supported by

  • NVIDIA Inception Program
  • ESC — European Society of Cardiology
  • American Heart Association
  • The Residency
  • Yale University School of Medicine
  • NYC EDC
  • Company Ventures

Backed by

  • Transpose Platform
  • Long Journey
  • Entrepreneurs First
  • Cornell Ignite
  • MedTech Innovator

Building the mammogram of the heart.

Breast cancer has mammograms. Colon cancer has colonoscopies. Heart disease has no routine early check. Lucentia turns a scan patients already get into one.

Contact us

Let's talk about your cardiac imaging.

Address
New York, NY
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